Anti-Inflammatory Activity of Selected Herbal Plants: A Critical Review
Activité Anti-Inflammatoire d'Une Sélection de Plantes Médicinales : Une Revue Critique
DOI:
https://doi.org/10.67260/hra.v4i7.7880Keywords:
Phytotherapy, Inflammation, Mechanisms of action, Medicinal plantsAbstract
Inflammation is a crucial feature in many acute and chronic diseases. There is a growing demand for anti-inflammatory remedies with fewer side effects compared to traditional drugs. In our review, we examined the anti-inflammatory properties of selected herbal plants that are well-known in both modern and traditional phytotherapy. These plants include Zingiber officinale (Ginger), Turmeric, Chamomile, Mentha (Mint), Thyme, and Green tea. We analyzed six to eight studies for each plant, sourced from PubMed or Google Scholar, to understand their anti-inflammatory effects. The review discusses the therapeutic significance and mechanisms of action for each plant. The studies show that these plants demonstrate anti-inflammatory effects in both in vivo and in vitro models. Their mechanisms involve regulating pro-inflammatory mediators and suppressing key signaling pathways such as COX-1, COX-2, and NF-kB, among others. The anti-inflammatory activities were evaluated using various assays, including protein denaturation, inhibition of cyclooxygenase and lipoxygenase, RT-PCR, ELISA for cytokine detection, Carrageenan-induced Paw Edema in rats, and Green Synthesis of Selenium Nanoparticles (SeNPs), among others. This research supports the potential of these plants as alternative and complementary therapies for managing inflammatory diseases. Further research and clinical trials are needed to standardize and confirm their therapeutic uses.
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