Prevalence of Acute Kidney Injury in Acute Geriatric Care in The Yaounde Central Hospital : A 3-Year Retrospective Study

Authors

  • Marie-Josiane Ntsama Essomba 1. Department of Internal Medicine and specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon
  • Massamba Ba 2. Department of Medicine and specialties, Faculty of Medicine, Pharmacy and Dental Medicine, Cheikh Anta Diop University, Dakar, Senegal
  • Raye Ngapout Amsetou 2. Department of Medicine and specialties, Faculty of Medicine, Pharmacy and Dental Medicine, Cheikh Anta Diop University, Dakar, Senegal
  • Nzana Victorine Bandolo 1. Department of Internal Medicine and specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon
  • Madeleine Ngandeu-Singwe 1. Department of Internal Medicine and specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon

DOI:

https://doi.org/10.5281/zenodo.19358088

Keywords:

acute kidney injury, older adults, geriatrics, Cameroon

Abstract

Introduction. Acute kidney injury (AKI) is a common complication among hospitalized older adults due to age-related decline in renal reserve, multimorbidity and exposure to acute stressors. This study aimed to determine the prevalence of AKI among older adults admitted to acute geriatric care in Cameroon. Patients and Methods. We conducted a cross-sectional study with retrospective data collection in the geriatric unit of the Yaoundé Central Hospital. Medical records of patients aged ≥65 years admitted between January 2022 and December 2024 were reviewed. Sociodemographic characteristics, clinical diagnosis, comorbidities, geriatric syndromes and hospital outcomes were collected. AKI was defined according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Results. A total of 167 patients were included with a median age of 79 years (IQR: 73–85). AKI occurred in 55 patients (32.9%). Sepsis was significantly more frequent among patients with AKI compared with those without AKI (43.6% vs 24.1%, P = 0.010). Geriatric syndromes were highly prevalent notably dependency (91.6%), frailty (86.8%), urinary incontinence (65.7%) and undernutrition (49.7%), but were not significantly associated with AKI. Overall in-hospital mortality was 17.4%, with a higher proportion among patients with AKI (23.6%) compared with those without AKI (14.3%). Conclusion. AKI is frequent among older adults admitted to acute geriatric care in Cameroon. Sepsis emerged as the main associated clinical condition. The high prevalence of geriatric syndromes underscores the importance of comprehensive geriatric assessment.

References

1. Summary of Recommendation Statements. Kidney Int Suppl [Internet]. 2012 Mar;2(1):8–12. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2157171615310443

2. Yokota LG, Sampaio B, Rocha EP, Balbi A, Sousa Prado I, Ponce D. Acute kidney injury in elderly patients: narrative review on incidence, risk factors, and mortality. Int J Nephrol Renovasc Dis [Internet]. 2018 Aug;Volume 11:217–24. Available from: https://www.dovepress.com/acute-kidney-injury-in-elderly-patients-narrative-review-on-incidence--peer-reviewed-article-IJNRD

3. Susantitaphong P, Cruz DN, Cerda J, Abulfaraj M, Alqahtani F, Koulouridis I, et al. World Incidence of AKI. Clin J Am Soc Nephrol [Internet]. 2013 Sep;8(9):1482–93. Available from: https://journals.lww.com/01277230-201309000-00006

4. Alba Schmidt E, De Rosa S, Müller J, Hüsing P, Daniels R, Theile P, et al. Acute kidney injury predicts mortality in very elderly critically-ill patients. Eur J Intern Med [Internet]. 2024 Sep;127:119–25. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0953620524001936

5. Pugh J, Aggett J, Goodland A, Prichard A, Thomas N, Donovan K, et al. Frailty and comorbidity are independent predictors of outcome in patients referred for pre-dialysis education. Clin Kidney J [Internet]. 2016 Apr;9(2):324–9. Available from: https://academic.oup.com/ckj/article-lookup/doi/10.1093/ckj/sfv150

6. Adu D, Okyere P, Boima V, Matekole M, Osafo C. Community-acquired acute kidney injury in adults in Africa. Clin Nephrol [Internet]. 2016 Dec 1;86(S1):48–52. Available from: https://www.dustri.com/article_response_page.html?artId=14639&doi=10.5414/CNP86S121&L=0

7. Danielle FMEEH, Berinyuy LC, Maimouna M, Bandolo NV, Emmanuel N, Francois KF. Clinical Profile and Outcome of Acute Kidney Injury in Elderly Adults in a Tertiary Hospital in Cameroon. Open J Nephrol [Internet]. 2020;10(04):311–22. Available from: https://www.scirp.org/journal/doi.aspx?doi=10.4236/ojneph.2020.104031

8. Katz S. Assessing Self-maintenance: Activities of Daily Living, Mobility, and Instrumental Activities of Daily Living. J Am Geriatr Soc [Internet]. 1983 Dec 1 [cited 2023 Feb 5];31(12):721–7. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/j.1532-5415.1983.tb03391.x

9. Rockwood K. A global clinical measure of fitness and frailty in elderly people. Can Med Assoc J [Internet]. 2005 Aug 30;173(5):489–95. Available from: http://www.cmaj.ca/cgi/doi/10.1503/cmaj.050051

10. Pereira M, Rodrigues N, Godinho I, Gameiro J, Neves M, Gouveia J, et al. Acute kidney injury in patients with severe sepsis or septic shock: a comparison between the ‘Risk, Injury, Failure, Loss of kidney function, End-stage kidney disease’ (RIFLE), Acute Kidney Injury Network (AKIN) and Kidney Disease: Improving Global Outcom. Clin Kidney J [Internet]. 2016 Dec 13;sfw107. Available from: https://academic.oup.com/ckj/article-lookup/doi/10.1093/ckj/sfw107

11. Halle MPE, Chipekam NM, Beyiha G, Fouda H, Coulibaly A, Hentchoya R, et al. Incidence, characteristics and prognosis of acute kidney injury in Cameroon: a prospective study at the Douala General Hospital. Ren Fail [Internet]. 2018 Oct 15;40(1):30–7. Available from: https://www.tandfonline.com/doi/full/10.1080/0886022X.2017.1419970

12. Ndjame AGN, Dieng A, Ngamby VE, Coume M, Ka EHF, Fall M, et al. Acute Renal Failure in the Elderly in the Nephrology Department of Aristide Le Dantec Hospital in Senegal: About 45 Cases. Open J Nephrol [Internet]. 2023;13(04):451–63. Available from: https://www.scirp.org/journal/doi.aspx?doi=10.4236/ojneph.2023.134041

13. Chong E, Chan M, Lim WS, Ding YY. Frailty Predicts Incident Urinary Incontinence Among Hospitalized Older Adults—A 1-Year Prospective Cohort Study. J Am Med Dir Assoc [Internet]. 2018;19(5):422–7. Available from: https://doi.org/10.1016/j.jamda.2017.12.103

14. Shi X, Wang S, Hu J, Chen F, Zhang H, Yang Y, et al. Relationship of Frailty with Kidney Function in Adults More Than 60-Years-Old: Effect of Using Different Formulas to Estimate Glomerular Filtration Rate. Clin Interv Aging [Internet]. 2023 Jun;Volume 18:999–1007. Available from: https://www.dovepress.com/relationship-of-frailty-with-kidney-function-in-adults-more-than-60-ye-peer-reviewed-fulltext-article-CIA

15. Marie-Josiane Ntsama Essomba RMMM, Ottou MZ, Madeleine, Singwe N. In-Hospital Mortality and Associated Factors in Acute Geriatric Care in Cameroon : A Retrospective Study. 2023;24(March):15–8. https://doi.org/10.5281/hsd.v24i2%20Suppl%201.4268

16. Bigna JJ, Noubiap JJ. The rising burden of non-communicable diseases in sub-Saharan Africa. Lancet Glob Heal [Internet]. 2019 Oct 1 [cited 2023 Jul 27];7(10):e1295–6. Available from: http://www.thelancet.com/article/S2214109X19303705/fulltext

17. Kaze AD, Ilori T, Jaar BG, Echouffo-Tcheugui JB. Burden of chronic kidney disease on the African continent: a systematic review and meta-analysis. BMC Nephrol [Internet]. 2018 Dec 1;19(1):125. Available from: https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-018-0930-5

18. Metanmo S, Kuate-Tegueu C, Gbessemehlan A, Dartigues J-F, Ntsama M-J, Nguegang Yonta L, et al. Self-reported visual impairment and sarcopenia among older people in Cameroon. Sci Rep [Internet]. 2022 Oct 21;12(1):17694. Available from: https://www.nature.com/articles/s41598-022-22563-9

19. Ntsama Essomba M-J, Mballa Mba RM, Ekwalla Kameni L, Tchebegna P, Mvondo Lema FD, Tabue-Teguo M. Prevalence of frailty and association with intrinsic capacity decline among community-dwelling older people in Cameroon: a cross sectional study. BMC Geriatr [Internet]. 2025 May 14;25(1):335. Available from: https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-025-06011-7

Downloads

Published

04/01/2026

How to Cite

Marie-Josiane Ntsama Essomba, Massamba Ba, Raye Ngapout Amsetou, Nzana Victorine Bandolo, & Madeleine Ngandeu-Singwe. (2026). Prevalence of Acute Kidney Injury in Acute Geriatric Care in The Yaounde Central Hospital : A 3-Year Retrospective Study. HEALTH RESEARCH IN AFRICA, 4(Suppl 1), 24–28. https://doi.org/10.5281/zenodo.19358088

Issue

Vol. 4 No. Suppl 1 (2026): Health Research in Africa

Section

Research Articles

License

Copyright (c) 2026 Marie-Josiane Ntsama Essomba, Massamba Ba, Raye Ngapout Amsetou, Nzana Victorine Bandolo, Madeleine Ngandeu-Singwe

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License  CC BY-NC-ND 4.0  that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work

Most read articles by the same author(s)

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.