Prevalence and Determinants of Gastroesophageal Reflux Disease in a Guinean University Setting: A Cross‑Sectional Study in Three Medical Schools
Prévalence et Déterminants du Reflux Gastro-Œsophagien en Milieu Universitaire Guinéen : Une Étude Transversale dans Trois Facultés de Médecine
DOI:
https://doi.org/10.5281/zenodo.19358466Keywords:
GERD-Prevalence-Risk factors-Students-GuineaAbstract
RÉSUMÉ
Introduction. Le reflux gastro-œsophagien (RGO) est une pathologie digestive fréquente, dont la survenue chez les étudiants en médecine est favorisée par le stress, des habitudes alimentaires irrégulières et certains comportements de vie. En Guinée, sa prévalence et ses facteurs de risque chez cette population restent méconnus. Notre étude a déterminé la prévalence et les facteurs associés au RGO chez les étudiants en médecine de Conakry. Méthodes. Cette étude transversale prospective a été menée d’août 2025 à janvier 2026 dans les trois facultés de médecine de Conakry. Tous les étudiants présents et consentants ont été inclus. Le diagnostic de RGO a été retenu sur la présence d’au moins un symptôme typique (pyrosis, régurgitations acides, syndrome postural). Les associations ont été analysées par régression logistique (p < 0,05). Résultats. Parmi les 527 participants (âge médian 22 ans, 51,6 % de femmes), la prévalence du RGO était de 38,9 % (205/527). Les symptômes typiques étaient dominés par le pyrosis (49,8 %). En analyse multivariée, les facteurs indépendamment associés au RGO étaient : le tabagisme (OR = 4,05 ; IC95 % : 1,27–13,9), la prise d’anti-inflammatoires non stéroïdiens (OR = 2,37 ; IC95 % : 1,51–3,72), le stress (OR = 1,84 ; IC95 % : 1,13–3,07), la consommation régulière de plats épicés (OR = 1,73 ; IC95 % : 1,10–2,75) et la consommation de chocolat (OR = 1,63 ; IC95 % : 1,03–2,63). Conclusion. Le RGO touche près de deux étudiants en médecine sur cinq à Conakry. Le tabagisme, la prise d’AINS, le stress, les plats épicés et le chocolat en sont les principaux facteurs de risque modifiables. Ces résultats plaident pour des actions de sensibilisation ciblées au sein des facultés.
ABSTRACT
Introduction. Gastroesophageal reflux disease (GERD) is a common digestive disorder, and its occurrence in medical students is promoted by stress, irregular eating habits, and certain lifestyle behaviors. In Guinea, its prevalence and risk factors in this population remain unknown. Our study determined the prevalence and factors associated with GERD among medical students in Conakry. Methods. This prospective cross‑sectional study was conducted from August 2025 to January 2026 in the three medical faculties of Conakry. All students present and consenting were included. GERD was diagnosed based on the presence of at least one typical symptom (heartburn, acid regurgitation, postural syndrome). Associations were analyzed using logistic regression (p < 0.05). Results. Among 527 participants (median age 22 years, 51.6% female), the prevalence of GERD was 38.9% (205/527). Typical symptoms were dominated by heartburn (49.8%). In multivariate analysis, factors independently associated with GERD were: smoking (OR = 4.05; 95% CI: 1.27–13.9), non‑steroidal anti‑inflammatory drug use (OR = 2.37; 95% CI: 1.51–3.72), stress (OR = 1.84; 95% CI: 1.13–3.07), regular consumption of spicy foods (OR = 1.73; 95% CI: 1.10–2.75), and chocolate consumption (OR = 1.63; 95% CI: 1.03–2.63). Conclusion. GERD affects nearly two in five medical students in Conakry. Smoking, NSAID use, stress, spicy foods, and chocolate are the main modifiable risk factors. These findings call for targeted awareness‑raising actions within medical faculties.
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Copyright (c) 2026 Diallo Djenabou, Sow Ousmane, Sant’anna Adéwoumi Peace Robincia1, Diallo Kadiatou, Diallo Mamadou Sarifou, Diallo Ahmed Tidiane, Sylla Djibril, Doumbouya Noumé Bella

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