Factors Associated with Health-Related Quality of Life in Cameroonian Adolescents Living with Perinatally Acquired HIV: A Cross-Sectional Study
Facteurs Associés À La Qualité de Vie Liée À la Santé Chez les Adolescents Camerounais Vivant avec le VIH périnatal : Une Étude Transversale
DOI:
https://doi.org/10.5281/zenodo.17968577Keywords:
Health-Related Quality of Life, Adolescents, Perinatally acquired HIV, Antiretroviral TherapyAbstract
ABSTRACT
Introduction. In most sub-Saharan African countries, interventions in pediatric HIV had focused on the medical treatment of the disease, with little emphasis on the long-term psychosocial issues. This study aimed to explore Health-Related quality Of Life (HR-QOL) and its associated factors among Adolescents Living with perinatally acquired HIV (ALHIV) on Antiretroviral Therapy (ART) and cared of in a reference hospital in Yaounde, Cameroon. Methodology. This was a cross-sectional analysis of baseline data set from the IAS-CIPHER-2021/1214-ATE SMAVI study. The participants enrolled in this study were 156 ALHIV, aged 15-19 years, on ART and cared of in the CME-FCB. The World Health Organization Quality of Life (WHOQOL)-HIV-BREF was used to assess HR-QOL among the study participants. The association of exposure variables with the mean score of HR-QOL for ALHIV was assessed in univariate and multivariate analysis using linear regression. Results. Among the 156 participants enrolled this study, 49.4% were female. Their mean (±Standard Deviation) age was 17.4 (±1.4) years. Most participants were having at least one parent alive (78.2%). Less than third of the participants presented with suffered from severe depression (29.5 %). The mean (±Standard Deviation) score of HR-QOL was 68.4 (±9.6). The HR-QOL remained significantly higher only in participants with both parents alive (p < 0.001) and significantly lower in participants suffering from moderate or severe depression (p < 0.001). Conclusion. More care and support should be given for orphans and those with severe depression whose quality of life is significantly worse.
RÉSUMÉ
Introduction. Dans la plupart des pays d'Afrique subsaharienne, les interventions en rapport avec le VIH pédiatrique sont plus orientées vers le traitement médical de la maladie, avec moins d'importance accordée aux problèmes psychosociaux à long terme. Cette étude visait à explorer la qualité de vie liée à la santé (QdV-S) et les facteurs associés chez les adolescents vivant avec le VIH périnatal (AvVIH) sous traitement antirétroviral (TAR) au Centre Mère et Enfant de la Fondation Chantal Biya à Yaoundé au Cameroun (CME-FCB). Méthodologie. Il s'agissait d'une analyse transversale des données initiales de l'étude IAS-CIPHER SMAVI. Les participants à cette étude étaient 156 AvVIH âgés de 15 à 19 ans et sous TAR au CME-FCB. La QdV-S a été mesurée à l’aide du questionnaire WHOQOL-HIV-BREF de l’OMS. A l’aide des modèles de régression linéaire, l'association entre les variables d'exposition et le score moyen de QdV-S chez les AvVIH a été évaluée. Résultats. Parmi les 156 participants à cette étude, 49,4% étaient des filles. Leur âge moyen (± écart-type) était de 17,4 (± 1,4) ans. La plupart des participants avaient au moins un parent vivant (78,2%). Moins d'un tiers des participants souffraient de dépression sévère (29,5 %). Le score moyen (± écart-type) de la QdV-S était de 68,4 (± 9,6). La QdV-S restait significativement plus élevée uniquement chez les participants dont les deux parents étaient en vie (p < 0,001) et significativement plus faible chez les participants souffrant de dépression modérée ou sévère (p< 0,001). Conclusion. Il convient d'accorder davantage d'attention et de soutien aux AvVIH orphelins et aux AvVIH souffrant de dépression sévère, dont la qualité de vie est nettement moins bonne.
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Copyright (c) 2025 Francis Ateba Ndongo, Justin Ndie, Désiré Aminou Sambo, Jean-Pierre Yves Awono Noah, Rogacien Kana, Marius Tchassep Nono, Patrice Ndzie, Alice Ketchaj, Hélène Kamo, Mathurin Cyrille Tejiokem, Emmanuelle Alexandra Hopp Biheng, Joseph Fokam, Roméo Bouba Yagai, Patrice Zanga Olinga, Calixte Ida Penda, Jérôme Ateudjieu, Paul Olivier Koki Ndombo, Hubert Désiré Mbassi Awa, Anne Cécile Zoung-Kanyi Bissek, Albert Faye, Philippe Msellati, Marc Lallemant
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