Renal Replacement Therapy in Critical Care Unit: Covid 19 Unit’s Experience of Treichville’s University Hospital (Abidjan – Cote d’Ivoire)

Thérapie de Remplacement Rénal en Unité de Soins Intensifs Chez des Patients Ivoiriens Porteurs de Covid 19 : Une Étude au Centre Hospitalier Universitaire de Treichville (Abidjan)

Authors

  • Adingra SCE 1. Felix Houphouet Boigny University, Cocody, Abidjan Ivory Coast, West Africa
  • Sai SS 1. Felix Houphouet Boigny University, Cocody, Abidjan Ivory Coast, West Africa
  • Kouame KI 1. Felix Houphouet Boigny University, Cocody, Abidjan Ivory Coast, West Africa
  • Kouame KA 1. Felix Houphouet Boigny University, Cocody, Abidjan Ivory Coast, West Africa
  • Diomande SE 1. Felix Houphouet Boigny University, Cocody, Abidjan Ivory Coast, West Africa
  • Kone K 1. Felix Houphouet Boigny University, Cocody, Abidjan Ivory Coast, West Africa
  • Konan N 1. Felix Houphouet Boigny University, Cocody, Abidjan Ivory Coast, West Africa
  • Safari B 3. Intensive Care unit of Treichville’s University Hospital (Ivory Coast)
  • Boua N 1. Felix Houphouet Boigny University, Cocody, Abidjan Ivory Coast, West Africa

DOI:

https://doi.org/10.67260/hra.v3i10.7049

Keywords:

Renal Replacement Therapy, Covid 19, ICU, Africa

Abstract

ABSTRACT
Introduction. Before the COVID-19 pandemic, renal replacement therapy was not performed in intensive care units in Abidjan, Côte d'Ivoire. The health crisis created a therapeutic imperative to manage severe acute kidney injury in this setting. This study aimed to describe the first experience with intermittent hemodialysis in the ICU for patients with severe COVID-19 at Treichville University Hospital. Methodology. A single-center retrospective study was conducted over one year at Treichville University Hospital. All adult COVID-19 patients with acute kidney injury (AKI) requiring hemodialysis in the ICU were included. Demographic, clinical, dialysis parameters, and outcomes were analyzed. Results. Among 416 patients admitted to the ICU, 97 had AKI (23.3%), of whom 30 (31%) required dialysis. The mean age was 53 years with a male predominance (sex ratio 5:1). No underlying chronic kidney disease was known in 83% of patients. AKI was moderate to severe (KDIGO >1) in 90% of cases. The anuria-metabolic acidosis-hyperkalemia triad was the main indication (70%). The average number of sessions was 2.4. Incidents included hypotension (n=12) and hypoglycemia (n=2). Mortality was 70%. Invasive ventilation (50%) and the use of vasoactive amines (46.6%) were significantly associated with death (p<0.05). Conclusion. The pandemic enabled the initiation of hemodialysis in the ICU in Abidjan. Despite this technical advance, mortality was high, strongly associated with the severity of the critical condition (invasive ventilation, vasoactive amines) rather than with dialysis itself.
.
RÉSUMÉ
Introduction. Avant la pandémie de COVID-19, l'épuration extrarénale n'était pas pratiquée en réanimation à Abidjan, Côte d'Ivoire. La crise sanitaire a créé un impératif thérapeutique pour prendre en charge l'insuffisance rénale aiguë sévère dans ce contexte. Cette étude vise à décrire la première expérience d'hémodialyse intermittente en réanimation chez des patients atteints de formes graves de COVID-19 au CHU de Treichville. Méthodologie. Une étude rétrospective monocentrique a été menée sur un an au CHU de Treichville. Tous les patients adultes COVID-19 avec insuffisance rénale aiguë (IRA) nécessitant une hémodialyse en réanimation ont été inclus. Les données démographiques, cliniques, les paramètres de dialyse et les outcomes ont été analysés. Résultats. Sur 416 patients admis en réanimation, 97 présentaient une IRA (23,3%), dont 30 (31%) ont été dialysés. L'âge moyen était de 53 ans avec une prédominance masculine (sex-ratio 5:1). Aucune néphropathie chronique sous-jacente n'était connue chez 83% des patients. L'IRA était modérée à sévère (KDIGO >1) dans 90% des cas. La triade anurie-acidosemétabolique-hyperkaliémie constituait la principale indication (70%). Le nombre moyen de séances était de 2,4. Les incidents incluaient hypotension (n=12) et hypoglycémie (n=2). La mortalité était de 70%. La ventilation invasive (50%) et l'utilisation d'amines vasoactives (46,6%) étaient significativement associées au décès (p<0,05). Conclusion. La pandémie a permis d'initier l'hémodialyse en réanimation à Abidjan. Malgré cette avancée technique, la mortalité est restée élevée, fortement associée à la gravité de l'état initial (ventilation invasive, amines vasoactives) plutôt qu'à la dialyse elle-même.

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Published

09/26/2025

How to Cite

Adingra SCE, Sai SS, Kouame KI, Kouame KA, Diomande SE, Kone K, … Boua N. (2025). Renal Replacement Therapy in Critical Care Unit: Covid 19 Unit’s Experience of Treichville’s University Hospital (Abidjan – Cote d’Ivoire): Thérapie de Remplacement Rénal en Unité de Soins Intensifs Chez des Patients Ivoiriens Porteurs de Covid 19 : Une Étude au Centre Hospitalier Universitaire de Treichville (Abidjan). HEALTH RESEARCH IN AFRICA, 3(10), 58–63. https://doi.org/10.67260/hra.v3i10.7049

Issue

Section

Urology - Nephrology

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